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We have many innovative medical technologies available for licensing across a broad range of domains and disciplines. From medical devices and pharmaceuticals to diagnostics and digital health, our portfolio showcases de-risked inventions with true market potential. A dedicated business development team member guides you toward the right solution for your problem and streamlines the licensing process.
We transform ideas into innovations that improve healthcare for people around the world. Cleveland Clinic Innovations currently has many technologies available for licensing across a broad range of disciplines and domains. All our technologies have undergone a rigorous process of ideation, assessment and development to optimize them for our investors.
Please click on the individual technology titles below to learn more.

Image-based Determination of Joint-Specific Movement Capacity and Motion Signature
Software for determining
joint-specific movement capacity
and motion signature.

Personalizing Chemotherapy Drug Selection Using a Transcriptomic Chemogram
Clinical decision support tool for
predicting and ranking
chemotherapy drug sensitivity on
an individual basis.

Aortic Valve Interventional Planning in Mixed Reality
Mixed reality tool for surgical
planning of aortic valve repair
/ replacement.

Continuous Right Ventricular Hemodynamic Monitoring
Comprehensive right ventricle
function monitoring.

3D Printed Patient-Specific Pedicle Screw Guide & Semi-Automated Planning Software for Accurate Spinal Placement and Optimal Screw Fixation
3D printed patient-specific
pedicle screw guide and a semiautomated planning software for
maximized screw fixation.

Manos Medication MonitoringProgram (M3P)
A platform for efficient ADHD
medication titration and
monitoring.
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Cleveland Clinic Postural Stability Index
Objective postural stability (PS)
metrics using body-worn inertial
sensors.
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Troop Readiness Evaluation with Augmented Reality Return-to Duty (READY) System
Augmented reality (AR) platform
to quantify cognitive and motor
performance during military
specific activities. Aids in the
detection mild traumatic brain
injury and facilitates appropriate
return-to-duty decision making.

eSports Athlete Performance Evaluation Application
Novel eSports athlete evaluation
for performance optimization and
injury prevention.

Automated Detection of Acute Aortic Syndromes via CT Image Analysis
Patented system and method
for the automated detection of
AAS from CT Images.
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Smart Phone Enabled Assessment of Timed Up and Go(TUG) Test
Smart phone application as a self-administered comprehensive tool for the assessment and quantification of overall mobility function.
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Voice Detect: A Novel Application that Detects Life-Threatening Conditions from the Human Voice
Voice analysis platform that captures patient voice samples to quickly identify life-threatening medical conditions that cause hoarseness.
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Algorithms for Prediction of Overactive Bladder Response to Third Line Treatment Options
A machine learning algorithm, used to predict patient outcomes following the overactive bladder treatment Onabotulinumtoxin A (OBTX-A) injection and sacral neuromodulation (SNM).

Machine Learning Algorithms to Predict Urine Culture Resistance to Antibiotics
Adaptable and dynamic machine learning algorithm that accurately predicts antibiotic resistance.

Situational Awareness Electronic Vital Scout (SAVES)
SAVES is an automated pediatric deterioration risk assessment and clinical decision support system.

VitalScout: EMR-Enhanced Early Warning System
VitalScout is a vital signs monitoring platform designed to simplify and automate complex tasks associated to patient care.

Skilled Nursing Facility (SNF) Mortality Model
A machine learning model created to predict 0–180-day mortality risk for patients being transferred from acute care to a skilled nursing facility.

Severity of Illness Scoring System (SASS)
Non-linear cardiovascular critical care scoring system for improved patient risk classification.

Strategic Workforce Planning: Role Redesign & Capacity Optimization
Systematic, analytical approach driven by data and algorithms for redesigning job tasks and roles.

Predicting Hypertension Control Using Machine Learning
System for effective management of hypertensive patient medication and dosage.

Microsurgical and Supermicrosurgical Decision Support System
An AI-based platform capable of processing images from intricate surgical procedures to offer real-time clinical decision support.

A Dynamic Approach to Decision-Making: Navigating Through Uncertainty with CyberGPS
Solution delivers actionable and transparent planning, implementation, and management for any organization’s dynamic cyber security priorities.

ViVE
We’re thrilled to be part of this year’s ViVE conference - where digital health decision-makers, innovators, and industry leaders gather to shape the future of healthcare. ViVE uniquely focuses on the business of transformation in healthcare, bringing together the best minds from C-suites, startups, policymakers, and solution providers.
Taking place in Nashville, a thriving hub for the healthcare industry, this event is the perfect opportunity to collaborate, network, and explore cutting-edge solutions. If you’re attending, connect with our and discuss how we can drive meaningful change together!
Connect with:
Sonja OMalley, MBA, PMP - omalles@ccf.org
JD Friedland, MBA - friedlj3@ccf.org
Todd Schwarzinger, MBA - schwart2@ccf.org
Jerry Wilmink, PhD, MBA - wilminj@ccf.org
AUTM
Our team is excited to be heading to the largest gathering of academic technology transfer professionals in the world at AUTM's 2025 Annual Meeting in Washington, D.C. AUTM is a time to connect, make deals, and gain insights from world-class speakers and panels.
BIO
Biotechnology Innovation Organization is the premier gathering of the global biotech community and we will be showcasing innovative technologies from our portfolio!
HLTH
Our team will be in Las Vegas from for HLTH 2025 diving into the latest trends in healthcare and showcase our groundbreaking innovations. We believe that strategic alliances are key to transforming innovative ideas into real-world solutions. Cleveland Clinic Innovations offers a diverse portfolio of innovative, healthcare technologies for licensing and partnership, supported by a dedicated team to navigate the process of going to market in various healthcare domains.
HLTH is forging ahead into new realms of possibilities, gathering 12,000+ influential leaders, executives and visionaries who are passionately creating the next generation of healthcare.
Expansion Across the Globe
Global Research, Education + Innovations
“Cleveland Clinic supports caregivers by fostering an environment of creativity and openness to explore how things can be done differently for the benefit for all patients. This culture of innovation is a core value that permeates throughout our entire ecosystem.”
Joseph Iannotti, MD, PhD
Chief Research and Academic Officer at Cleveland Clinic Florida
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